XI-w2 Frostbite
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Treatment of Frostbite

                     Introduction

Frostbite is the freezing of tissue and may involve only superficial tissues or may extend to the bone. 
The onset and severity of frostbite may be affected by air temperature, wind speed, duration of exposure, 
amount of exposed area, and predisposing conditions such as:

· *Poor or inadequate insulation from the cold or wind;

· *Immersion;

· *Altitude;

· *Impaired circulation from tight clothing or shoes;

· *Fatigue;

· *Injuries;

· *Circulatory disease;

· *Poor nutrition;

· *Dehydration;

· *Hypothermia;

· *Alcohol or drug use; and

· *Use of tobacco products.


Damage to the frostbitten tissues is caused by crystallization of water within the tissues, typically

between the cells, and by resulting changes in electrolyte concentration within the cells. Damage

occurs during the freezing process. Further damage occurs during reperfusion of frostbitten tissue.

Frostbite is frequently seen in Alaska , although, in most circumstances, the frostbite is superficial

and treated by the patient at home. Occasionally, it is severe enough to warrant transport to a

medical facility for evaluation and treatment. Seldom will it be necessary for emergency medical

personnel to perform in-field rewarming for deep frostbite. It may, however, be necessary to treat

patients with superficial frostbite who have sustained other injuries, (e.g. a motor vehicle crash

patient who has been exposed to sub-zero temperatures while awaiting the arrival of rescue and

medical personnel).


F
ROSTBITE

General Points

A). Hypothermia and other life threatening conditions may be present in the patient with

frostbite and must be evaluated and treated immediately.

B). When caring for a patient in extremely cold temperatures, take great care to prevent

hypothermia. Protect tissues from becoming frostbitten, and already frostbitten tissues from

worsening.

C). If the decision has been made not to rewarm frostbitten tissue in the field, it should be

protected, during transport, from additional injury and temperature changes.

D). Superficial frostbite affects the dermis and shallow subcutaneous layers of the part

exposed, and is recognized by white or gray colored patches. The affected skin feels firm,

but not hard. The skin initially turns red and, once frostbitten, is not painful. No deep tissue

loss will occur when treated with rapid rewarming.

E.) Deep frostbite affects the dermal and subdermal layers and may involve an entire digit or

body part. The skin feels hard and cold and the affected tissue is white or gray. A pulse

cannot be felt in the deeply frostbitten tissue and skin will not rebound when pressed.

F). Large blisters on the frostbitten area indicate that deep frostbite has partially or totally

thawed.

G.) Treatment of deep frostbite may be painful and is best accomplished in a medical facility.

Before electing to rewarm frostbitten tissue in the field, advice should be sought by radio or

telephone, if possible, from a physician who is knowledgeable about field treatment of

frostbite.

If transport time will be short (1-2 hours at most), the risks posed by improper

rewarming or refreezing outweigh the risks of delaying treatment for deep frostbite.

If transport will be prolonged (more than 1-2 hours), frostbite will often thaw

spontaneously. It is more important to prevent hypothermia than to rewarm frostbite rapidly

in warm water. This does not mean that a frostbitten extremity should be kept in the cold to

prevent spontaneous rewarming. Anticipate that frostbitten areas will rewarm as a

consequence of keeping the patient warm and protect them from refreezing at all costs.

H). Tissue which is thawed and then refrozen almost always dies. Consequently, the decision to

thaw the frostbitten tissue in the field commits the provider to a course of action which may

involve pain control, maintaining warm water baths at a constant temperature, and

protecting the tissue from further injury during rewarming and eventual transport. Once an

extremity is rewarmed in the field, it should not be used for ambulation.

I). In most cases, the patient should be transported as promptly as circumstances allow. When

frostbite is mild and is not complicated by other injuries, and there are resources available to

care for the patient without transport, it may be appropriate not to transport the patient to a

medical facility. This should only be done in consultation with a physician who is

knowledgeable about the treatment of frostbite. The decision not to transport should be

carefully documented by the prehospital provider, as with any such decision.

*

J.) Cautions:

1. do not rub the frozen part;

2. do not allow the patient to have alcohol or tobacco;

3. do not apply ice or snow;

4. do not attempt to thaw the frostbitten part in cold water;

5. do not attempt to thaw the frostbitten part with high temperatures such as those

generated by stoves, exhaust, etc.; and

6. do not break blisters which may form.

K). Frostbitten tissues should be handled extremely gently before, during, and after rewarming
.

L). When moving patients with frostbite by helicopter, care must be taken to protect the

patient from additional exposure to cold due to the increased windchill caused by

rotorwash. Rotorwash can be minimized if the helicopter shuts down while loading and

unloading. If this is unsafe from an aviation standpoint, the patient must be packaged

carefully to avoid any additional loss of heat or skin exposure that can cause or worsen

frostbite and hypothermia.

*

FROSTBITE

First Responder/Emergency Medical Technician-I, II, III/Paramedic

Small/Bush Clinic

Evaluation and Treatment

A. Anticipate, assess and treat the patient for hypothermia, if present.

B. Assess the frostbitten area carefully since the loss of sensation may cause the patient to be

unaware of soft tissue injuries in that area.

C. Obtain a complete set of vital signs and the patient's temperature.

D. Remove jewelry and clothing, if present, from the affected area.

E. Obtain a patient history, including the date of the patient's last tetanus immunization.

F. If there is frostbite distal to a fracture, attempt to align the limb unless there is resistance.

Splint the fracture in a manner which does not compromise distal circulation.

G. Determine whether rewarming the frostbitten tissue can be accomplished in a medical

facility. If it can, transport the patient while protecting the tissue from further injury from

cold or impacts.

H. If the decision is made to rewarm frostbitten tissue in the field, you should prepare a warm

water bath in a container large enough to accommodate the frostbitten tissues without them

touching the sides or bottom of the container. The temperature of the water bath should be

99° - 102 °F (37-39° C).

Generally patients with frostbite do not require opiates for pain relief; they occasionally

need non-opiate pain medication or anxiolytics. If possible, consult a physician regarding

the administration of oral analgesics, such as acetaminophen, ibuprofen or aspirin. Aspirin

or ibuprofen may help improve outcomes by blocking the arachadonic acid pathway.

Immersion injury or frostbite with other associated injuries may produce significant edema

and high pain levels. These patients may need opiate pain medications for initial treatment.

In this case, advanced life support personnel should administer morphine or other analgesics

in accordance with physician signed standing orders or on- line medical control.

I. A source of additional warm water must be available.

J. Water should be maintained at approximately at 99-102 °F (37-39 oC)* and gently circulated

around the frostbitten tissue until the distal tip of the frostbitten part becomes flushed.

K. Pain after rewarming usually indicates that viable tissue has been successfully rewarmed.

L. After rewarming, let the frostbitten tissues dry in the warm air. Do not towel dry
.

M. After thawing, tissues that were deeply frostbitten may develop blisters or appear cyanotic.

Blisters should not be broken and must be protected from injury.

* Please note that the new temperatures are lower than previously recommended, this decreases pain for the patient,

while only slightly slowing rewarming.


N. Pad between affected digits and bandage affected tissues loosely with a soft, sterile dressing.

Avoid putting undue pressure on the affected parts.

O. Rewarmed extremities should be kept at a level above the heart, if possible.

P. Protect the rewarmed area from refreezing and other trauma during transport. A frame

around the frostbitten area should be constructed to prevent blankets from pressing directly

on the injured area.

Q. Do not allow an individual who has frostbitten feet to walk except when the life of the

patient or rescuer is in danger. Once frostbitten feet are rewarmed, the patient becomes

nonambulatory.

*

FROSTBITE

Hospital

The following section covers general points and gives an overview of hospital treatment for

frostbite. This section is not intended to give complete information. Medical care providers who

are not experienced in the management of frostbite should consult a physician who regularly

manages frostbite and should consider transfer of the patient to a facility experienced in the care of  frostbite after the patient has been stabilized, if possible.

*

Evaluation and Treatment

A. Anticipate hypothermia. Assess and treat accordingly. Treat moderate to severe

hypothermia before treating the frostbitten areas, but don’t take so long that the extremities

thaw spontaneously. It may be possible to thaw the extremities and treat hypothermia

simultaneously, by combining peritoneal dialysis with rapid rewarming in a tub.

B. Assess frostbitten areas carefully, since the loss of sensation may cause the patient to be

unaware of soft tissue injuries in that area.

C. Obtain a complete set of vital signs and the patient's temperature
.

D. Obtain a patient history, including the date of the patient's last tetanus immunization if

possible. Give anti-tetanus therapy when indicated.

E. Remove jewelry and clothing, if present, from the affected area.

F. Give aspirin or ibuprofen.

*

G. Water should be maintained at approximately 99-102°F (37-39oC) and gently circulated

around the frostbitten tissue until the distal tip of the frostbitten part becomes flushed.8

H. Pain after rewarming usually indicates that viable tissue has been successfully rewarmed.

I. Pain relief:

· *Generally patients with frostbite do not require opiates for pain relief; they occasionally

need anxiolytics or aspirin.

· *Sympathectomy has been performed in some patients. Patients who received

sympathectomy have reported less pain, had a marked decrease in swelling, and tissue

separation occurred earlier and was more distal. Treatment with this method is still

controversial, and the results are variable.

· *Immersion injury, or frostbite with other associated injuries, may produce significant

edema and high pain levels. These patients may need epidural blockade (occasionally

for several days).

J. After re-warming, let the frostbitten tissues dry in the warm air. Do not towel dry.

K. After thawing, tissues that were deeply frostbitten may develop blisters or appear cyanotic.

L. Do not allow an individual who has frostbitten feet to walk except when the life of the

8 Please note that the new temperatures are lower than previously recommended. This decreases pain for the

patient, while only slightly slowing rewarming.

patient or rescuer is in danger. Once frostbitten feet are rewarmed, the patient becomes

nonambulatory.

M. Wound Care:

· *After thawing, if the injury is deep, use sterile sheets with cradles over extremity to

prevent additional trauma. Cotton pledgets between affected fingers/toes without

excessive pressure on the digital vessels helps prevent decreased circulation.

· *The clinician must decide if the extremity should be elevated (e.g. hanging frostbitten

arms in stockinette dressings) to reduce swelling or kept at the level of the heart to assist

blood flow in the small arterioles. Avoid keeping the tissues in a dependent position.

Examine the blood flow into the extremity at consistent intervals.

· *Blisters are generally left intact (usually sterile). Some experts aspirate small blisters

that contain reddish or bluish material using sterile technique to remove toxins.

· *Treatment is open; no wet dressings, ointments, occlusive dressings etc. If the patient

has severe pain, silver nitrate 0.5% can be used on the frostbitten area. If there are open

wounds secondary to the freezing injury 1% silver sulfadizine cream may be used.

· *Whirlpool baths twice daily. The water temperature should be body temperature (98oF /

37oC) which allows the part to be cleansed and removes superficial bacteria without

surgical debridement. Surgical soaps should be used in the baths (e.g. Betadine®, etc.).

· *When an eschar (scab) forms (usually on day 10-14), it is split manually to relieve

stiffness. Patients should perform bedside exercises of all small joints.

· *Delay debridement or amputations for at least 21 days, unless it is absolutely necessary.

There is less tissue retraction after this time (Premature amputation may cause the loss

of up to 3-5 cm)

· *Cover the wounds as soon as possible with split thickness (mesh) skin grafts

· *Antibiotics are not usually necessary unless deep infection is diagnosed.

· *Hyperbaric oxygen has not yet been shown to be beneficial in the final outcome of

frostbite, but may hasten wound healing.

M. If the lower extremity is frozen for a great length of time, the patient may develop a

compartment syndrome, most commonly in the anterior tibial compartment and the foot. If

compartment pressures are greater than 37-40 mm Hg, the skin may need to be split or the

patient may require a fasciotomy. Delay in performing fasciotomies can be disastrous.

N. Technetium99 studies can be useful to determine blood supply (Doppler ultrasound is not as

useful).

O. Smoking is discouraged as it causes small arterioles to constrict; alcohol is permitted.

P. Biofeedback may increase hand and foot circulation.

Q. Dibenzyline 10 mg once daily, which can be increased up to 20-60 mg, helps to treat

vasospasm and is a very effective alpha-adrenergic blocking agent.

R. TPA has not been found to be useful in these patients.

S. If there are associated fractures and dislocations:

· *Reduce dislocations immediately after thawing.

· *Treat fractures conservatively until thawed and placed in splint. Reduction or open

reduction can be done afterwards. These injuries tend to do poorly as the vascular blood

supply was embarrassed twice.

T. Children’s’ cartilage is more susceptible to cold injury. This is especially true in the carpal

and tarsal bones. This is due to the epiphyseal growth plates being still open. Injury may

occur in a child at any age at which the cartilage still persists.

U. If treatment has failed, and an amputation is needed, do modified guillotine amputations,

even in the digits.

*

Our thanks to the State of Alaska – Cold Injuries Guidelines